Korean Journal of Medicine  2015;89(5):581-584

doi:10.3904/kjm.2015.89.5.581

Myeloid Sarcoma of Peritoneum in Acute Myeloid Leukemia Patient with Inversion of Chromosome 16.

Ji Yoon KIM 1 ; Byeong Kyu PARK ; Sung Hwa BAE ; Hun Mo RYOO ; Woo Jung SUNG ; A Jin LEE

Affiliations

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Keywords

Sarcoma, Myeloid; Leukemia, Myeloid, Acute; Inv (16) fusion protein, Human

Country

Republic of Korea

Language

Korean

Abstract

Myeloid sarcoma is an extramedullary myeloid neoplasm that usually involves the skin, soft tissues, and lymph nodes. Myeloid sarcoma is found in 2.5-9.1% of acute myeloid leukemia patients, usually those with t (8;21), while inv (16) is rarely associated with myeloid sarcoma. Consequently, little is known of the characteristics and incidence of inv (16) in myeloid sarcoma. Myeloid sarcoma in acute myeloid leukemia patients with inv (16) is most often found in the abdominal lesions; the intestinal tract is involved most commonly, in the form of a mass. Here, we report an unusual myeloid sarcoma presenting as peritoneal carcinomatosis in acute myeloid leukemia with inv (16) that appeared to be ascites.