Journal of Korean Society of Pediatric Endocrinology  2011;16(3):185-188

doi:10.6065/jkspe.2011.16.3.185

Pituitary Hyperplasia Secondary to Hypothyroidism Caused by Hashimoto's Thyroiditis in a Female Adolescent.

Jeoung Suk KIM 1 ; Min Sun KIM ; Sun Jun KIM ; Gyung Ho CHUNG ; Pyoung Han HWANG ; Dae Yeol LEE

Affiliations

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Keywords

Pituitary gland; Hyperplasia; Hypothyroidism

Country

Republic of Korea

Language

English

Abstract

The authors report a case of a 16-year-old girl with pituitary hyperplasia and primary hypothyroidism caused by Hashimoto's thyroiditis. She presented with growth arrest, and hormonal studies showed decreased level of free thyroxine (T4), and increased levels of thyroid-stimulating hormone (TSH) and prolactin. A pituitary magnetic resonance imaging (MRI) showed a suprasellar mass. After 2 months of thyroxine replacement, thyroid function and high prolactin levels normalized, and the pituitary hyperplasia disappeared. This case represents relatively rapid normalization of pituitary hyperplasia, compare to the previous studies.