Journal of Periodontal & Implant Science  2014;44(4):207-213

doi:10.5051/jpis.2014.44.4.207

Micronutrients and superoxide dismutase in postmenopausal women with chronic periodontitis: a pilot interventional study.

Sunita DAIYA 1 ; Rajinder Kumar SHARMA ; Shikha TEWARI ; Satish Chander NARULA ; Paramjeet KUMAR SEHGAL

Affiliations

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Keywords

Antioxidants; Clinical trial; Chronic periodontitis; Root planning

Country

Republic of Korea

Language

English

Abstract

PURPOSE: The study was aimed at investigating changes in periodontal parameters and superoxide dismutase activity triggered by root surface debridement with and without micronutrient supplementation in postmenopausal women. METHODS: Forty-three postmenopausal chronic periodontitis patients were divided into two groups: group 1 (n=22) were provided periodontal treatment in the form of scaling and root planing (SRP) and group 2 (n=21) patients received SRP along with systemic administration of micronutrient antioxidants. Patients in both groups were subjected to root surface debridement. Group 2 patients also received adjunctive micronutrient antioxidant supplementation. Serum and salivary superoxide dismutase (SOD) activity along with periodontal parameters were recorded at baseline and 3 months after therapy. RESULTS: Salivary and serum SOD values significantly (P<0.05) improved with periodontal treatment. Improvement in systemic enzymatic antioxidant status along with reduction in gingival inflammation and bleeding on probing (%) sites was significantly greater in group 2 as compared to group 1. CONCLUSIONS: Adjunctive micronutrient supplements reduce periodontal inflammation and improve the status of systemic enzymatic antioxidants in postmenopausal women.