Korean Journal of Clinical Neurophysiology  2014;16(1):35-38

doi:10.14253/kjcn.2014.16.1.35

Japanese-B Viral Encephalitis with a Biphasic Illness Pattern and Recovery after Intravenous Immunoglobulin Therapy.

Byung Chan LEE 1 ; Ji Ye JEON ; Hye Jin MOON ; Jeong Geun LIM ; Yong Won CHO

Affiliations

+expand

Keywords

Japanese-B viral encephalitis; IVIG; Biphasic illness

Country

Republic of Korea

Language

Korean

Abstract

Japanese-B viral encephalitis (JE) usually has a monophasic illness pattern. A 45-year-old woman in an altered mentality had improved over 1 month. About 1 week after the initial improvement, the patient became comatose with aggravated EEG and MRI findings. Assays of cerebrospinal fluid and serum were positive for the IgM antibody to Japanese-B virus. After intravenous immunoglobulin (IVIG) infusion, the patient recovered. We report a patient with JE who showed a biphasic illness pattern and recovered after IVIG therapy.