Journal of Pharmaceutical Practice 2020;38(6):492-495

doi:10.12206/j.issn.1006-0111.202007063

Application and prospect of Humulus lupulus L. in anti-osteoporosis

Xiaoyan LIU 1 ; Tianshuang XIA 1 ; Zhimin DONG 2 ; Yiping JIANG 1 ; Luping QIN 3 ; Hailiang XIN 1

Affiliations

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Keywords

Humulus lupulus; chemical constituents; osteoporosis

Country

China

Language

Chinese

Abstract

Humulus lupulus is a kind of special resource plant used both as medicine and food in Xinjiang. In addition to being widely used in beer brewing, Humulus lupulus has long been recognized for its medicinal value, especially for the treatment of postmenopausal osteoporosis. Modern pharmacological research shows that its active components have great potential in the development of anti-osteoporosis drugs. However, in recent years, the wild Humulus lupulus resources in China have been seriously degraded, and the contents of active components are quite different. Ensuring high-quality Humulus lupulus germplasm resources is a prerequisite for the development and utilization of Humulus lupulus. This paper reviews the major chemical components of Humulus lupulus and their effects and application in the prevention and treatment of osteoporosis, and discusses the existing problems, aiming to provide a reference for the development and utilization of Humulus lupulus against osteoporosis.