Journal of Pharmaceutical Practice 2020;38(6):481-484

doi:10.12206/j.issn.1006-0111.202003055

Causes of liver injury in patients with COVID-19 and treatment with hepatoprotective drugs

Jin ZHANG 1 ; Wenjing ZHANG 2

Affiliations

+expand

Keywords

SARS-CoV-2; COVID-19; liver injury; inflammation; cytokine storm

Country

China

Language

Chinese

Abstract

COVID-19 patients infected with SARS-CoV-2 showed different degrees of liver injury. A series of studies have shown that cytokine storm, bile duct cell injury caused by SARS-CoV-2 and drug-induced hepatotoxicity can induce secondary liver injury. This article will review the mechanism of liver injury caused by different factors and the treatment of hepatoprotective drugs, in order to provide reference support for further research in this field.