The Korean Journal of Gastroenterology  2007;49(5):331-335

A Case of Photodynamic Therapy for Early Esophageal Cancer Recurred after Esophagectomy.

Byeong Wha HA 1 ; Jin Il KIM ; Eun Mi HWANG ; You Kyoung OH ; Dae Young CHEUNG ; Soo Heon PARK ; Jae Kwang KIM ; Kyu Yong CHOI

Affiliations

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Keywords

Photodynamic therpy; Early esophageal cancer; Second primary malignancy

Country

Republic of Korea

Language

Korean

Abstract

Photodynamic therapy is a promising modality for the palliation of advanced upper gastrointestinal cancer and for the eradication of early neoplastic and pre-neoplastic lesions. It is based on the combination of a photosensitizer that is selectively localized in the target tissue and illumination of the lesion with visible light, resulting in photodamage and subsequent cell death. For early esophageal cancer, esophagectomy has been a standard modality of curative intent. However, accumulated data supports the possibility of PDT replacing surgery as a curative modality. We experienced a case of early esophageal cancer that recurred after esophagectomy. The patient was successfully treated with photodynamic therapy using porfimer sodium as a photosensitizer.