The Korean Journal of Hepatology  2004;10(4):308-312

Porphyria Cutanea Tarda Presenting as Jaundice.

Kwang Hyuk PARK 1 ; Dong Yang PARK ; Jin Bae KIM ; Il Hyun BAEK ; Myung Seok LEE ; Gwang Ho BAIK ; Sang Hoon PARK ; Jong Hyeok KIM ; Choong Kee PARK ; Kwang Ho KIM

Affiliations

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Keywords

Porphyria cutanea tarda; Jaundice; Photosensitivity

Country

Republic of Korea

Language

Korean

Abstract

Porphyria cutanea tarda (PCT) is a disease characterized by an early appearance of severe photosensitivity with an increase in urinary uroporphyrin excretion and other porphyrins, high isocoproporphyrin fecal levels and an accumulation of protoporphyrin in erythrocyte. This disease has been known to be caused by a dramatic decrease in the activity of the uroporphyrinogen decarboxylase. Multiple infectious and environmental factors may contribute to PCT by influencing oxidative stress in the hepatocytes. We report here on a case of porphyria cutanea tarda that presented with jaundice and photosensitivity.