Organ Transplantation 2020;11(3):344-

doi:10.3969/j.issn.1674-7445.2020.03.004

Progress of immunosuppressant management, infection prevention and treatment after liver transplantation in severe liver disease

Han LI 1 ; Yanan JIA ; Qiang HE ; Xianliang LI

Affiliations

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Keywords

Liver transplantation; Liver failure; Severe liver disease; Multiple organ failure; Hepatic encephalopathy; Infection; Immunosuppressant; Multi-drug resistant bacteria

Country

China

Language

Chinese

Abstract

Liver transplantation is an effective treatment of severe liver disease. However, the pathophysiological changes of patients with severe liver disease are complicated, which significantly increase the difficulty of perioperative management of liver transplantation. Therefore, it is of great significance to strengthen postoperative management of the recipients with severe liver disease after liver transplantation. In this article, the pathophysiological characteristics of severe liver disease, the selection of immunosuppressant after liver transplantation, and the prevention and treatment of infection after liver transplantation in patients with severe liver disease were summarized.