Organ Transplantation 2020;11(3):326-

doi:10.3969/j.issn.1674-7445.2020.03.002

Clinical progress of diagnostic and evaluation criteria for liver transplantation in patients with severe liver disease

Yanan JIA 1 ; Han LI ; Xianliang LI ; Qiang HE

Affiliations

+expand

Keywords

Severe liver disease; Liver failure; Scoring system; Liver transplantation; Diagnostic criteria; Evaluation criteria; Child-Turcotte-Pugh (CTP) score; Model for end-stage liver disease (MELD) score

Country

China

Language

Chinese

Abstract

Liver transplantation, although recognized as the only effective radical treatment for severe liver disease, might be accompanied by high surgical risks, high perioperative mortality and high postoperative complications. Considering the shortage of donor liver and related surgical risks, it is necessary to strictly control the indication of operation and the opportunity of transplantation. Therefore, accurate diagnosis and comprehensive evaluation of the condition of patients with severe liver disease to be treated by liver transplantation is an important part in determining the treatment plan. At present, there are many evaluation criteria for severe liver disease. In addition to the classic ChildTurcotte-Pugh (CTP) score and model for end-stage liver disease (MELD) score, many other evaluation criteria have also been developed. All transplant centers have their own choices and thus there is no uniform diagnostic criterion, with disputes among various criteria, which is exactly what this paper aims to summarize.