Journal of Preventive Medicine 2019;31(7):649-652
doi:10.19485/j.cnki.issn2096-5087.2019.07.001
A case control study of risk factors for lung cancer
Yirong FANG 1 ; Yan MA ; Shuhong XU ; Yingxin PEI
Affiliations
Keywords
Lung cancer,Risk factors,Case-control study
Country
China
Language
Chinese
Abstract
Objective:To analyze the risk factors for lung cancer and to provide scientific evidence for prevention of lung cancer.
Methods:A total of 461 newly diagnosed patients with primary lung cancer from January 2015 to June 2017 in Shaoxing were selected as the case group. Six hundred healthy residents with the same residence,distribution of gender and age as the cases were selected as the control group by frequency matching method. A questionnaire survey was conducted to collect demographic characteristics,family history of major chronic diseases,disease history and behavioral factors. The method of case-control study and multivariate logistic regression model were used for statistical analysis of the risk factors for lung cancer.
Results: The results of multivariate logistic regression analysis showed that after adjusting for age and gender,family history of cancer(OR=6.606,95%CI:3.439-12.689),history of lung diseases(OR=2.836,95%CI:1.208-6.659),high level of stress(OR=2.485,95%CI:1.830-3.376),low consumption of fresh vegetables(OR=3.116,95%CI:2.470-3.930)and smoking(OR=6.029,95%CI:3.716-9.783)were risk factors for lung cancer;after adjusting for age,gender,family history of cancer,history of lung diseases,stress levels and consumption of fresh vegetables,quitting smoking for less than ten years was a risk factor for lung cancer(OR=4.751,95%CI:2.404-9.386)compared with quitting smoking for ten years or above.
Conclusion:Family history of cancer,history of lung diseases,high level of stress,low consumption of fresh vegetables and smoking were risk factors for lung cancer.
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