Chinese Journal of Applied Clinical Pediatrics 2019;34(13):970-975

doi:10.3760/cma.j.issn.2095-428X.2019.13.002

Research progress in genetic mechanism for congenital heart disease

Huichao SUN 1 ; Jie TIAN

Affiliations

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Keywords

Congenital heart disease; Genetics; Chromosome; Gene

Country

China

Language

Chinese

Abstract

Congenital heart disease (CHD) is the most common birth defect and is also the leading cause of death in infants and young children.Studying the pathogenesis of CHD and preventing the development of CHD are major scientific problems that need to be solved urgently.Now, it is known that the occurrence of CHD is caused by multiple factors such as genetic factors and environmental factors.In this paper, the genetic mechanisms in the progress of CHD were summarized.