PURPOSE: The purpose of this study was to identify the factors influencing on burnout in operating room nurses.METHODS: Using a cross-sectional design, a total of 109 operating room nurses working at 7 general hospitals with 300 beds or more in B city were analyzed. The instruments used for this study assessed job stress, resilience, professional identity, and burnout. Data was analyzed using descriptive statistics, a t-test, an ANOVA, a Pearson's correlation coefficient and a multiple regression analysis.RESULTS: There was a statistically significant correlation between burnout and job stress (r=.53, p < .001), resilience (r=-.59, p < .001), and professional identity (r=-.47, p < .001). The factors influencing burnout include job stress (β=.27, p < .001), resilience(β=-.37, p < .001), dissatisfaction with the nursing job (β=.32, p < .001), and moderate satisfaction with the nursing job (β=.19, p=.014), and the explanatory power was 53.0%.CONCLUSIONS: The results suggest that intervention to reduce job stress and to improve resilience, which were the factors influencing burnout in operating room nurses, is necessary.