Korean Journal of Family Practice 2019;9(1):83-88

doi:10.21215/kjfp.2019.9.1.83

Correlation between Serum Uric Acid and Bone Mineral Content in Healthy Women

Sung Moon CHO 1 ; Deok Hyun SHIN ; Ji In JUNG ; Kyu Nam KIM ; Seon Yeong LEE ; Jong Woo KIM ; Jeong Ki PAEK

Affiliations

+expand

Keywords

Female; Body Mass Index; Uric Acid; Bone Mineral Content

Country

Republic of Korea

Language

Korean

Abstract

BACKGROUND: Osteoporosis is a systemic skeletal disease characterized by reduced bone mineral density and skeletal microstructural abnormalities. We investigated the correlation between serum uric acid (SUA) levels and bone mineral content (BMC) values as a surrogate marker of bone health. Additionally, we assessed whether the correlation, if any, was evident even after classifying the study population into two groups based on a diagnosis of obesity in these individuals.METHODS: This study included 936 women who visited the healthcare centers that participated in this study. Fasting blood samples were obtained from all women to measure SUA, BMC of the lumbar spine was measured using dual-energy X-ray absorptiometry. We evaluated the correlation between SUA and BMC in obese and non-obese groups.RESULTS: SUA concentration and BMC were positively correlated (β=0.257, P=0.001); however, this correlation was significant only in the obese group (β=0.203, P=0.001).CONCLUSION: SUA concentration and BMC are positively correlated in women diagnosed obesity.