Abstract: This research was motivated by the increase of brain MRI examinations in emergency medicine. In an emergency, patients are often uncooperative, and they raise motion artefact on the image. Therefore, fast scanning techniques such as pulse Sequence Single Shot Fast Spin Echo (SS-FSE) is required to reduce the artefact. This study was conducted to determine the effectiveness of using SS-FSE technique to minimize motion artefact. Methods: This study was an observational analytic with prospective methods. Scanning was conducted to 16 normal patients (volunteers). Two neuro radiologists retrospectively and independently reviewed all images. Observations used standard diagnostic of brain MR Image by evaluating the anatomical and morphological structure. Results: Based on the results of the analysis of each organ that was assessed, it was obtained that the average of the image for overall organs on the brain; 76% looks sharp, 21% looks moderate (minimum blurred), and 3% looks blurred. Conclusion: SS-FSE technique affects reducing motion artefact due to object movement in MRI brain. The overall image SS-FSE produced has good image quality.