Dementia and Neurocognitive Disorders  2015;14(2):83-86

doi:10.12779/dnd.2015.14.2.83

Posterior Cortical Atrophy with Acute Onset and Rapid Progressive Visual Symptoms: A Case Report.

Jaejeong JOO 1 ; Sul Ki LEE ; In Ha HWANG ; Kyum Il KWON ; Byoung June AHN ; Youngsoon YANG

Affiliations

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Keywords

posterior cortical atrophy; rapid progression; visuo-spatial dysfunction

Country

Republic of Korea

Language

English

Abstract

BACKGROUND: Posterior cortical atrophy (PCA) is characterized by slowly progressive early onset dementia with cortical visual dysfunction and disproportionate atrophy of the posterior cortex. CASE REPORT: A 55-year-old right-handed woman developed visuo-spatial impairments that progressed rapidly into cortical blindness over the following 3 months. Neuro-psychological evaluation revealed Gerstmann syndrome and severe constructional impairments with all components of Balint syndrome. However, her memory, insight, and judgment were preserved. Her brain MRI was normal. However, 18F fluorodeoxyglucose positron emission tomography revealed a marked hypometabolism in the bilateral parieto-occipital region. CONCLUSIONS: Although rapid progression of visuo-spatial dysfunction without memory impairment occurred, we considered PCA as well.