Journal of Shenyang Medical College 2016;18(3):132-134

doi:10.16753/j.cnki.1008-2344.2016.03.002

Effect of Ginseng Polysaccharides on Growth and Proliferation of Different Tumor Cells

Han HAN 1 ; Guangjun GANG ; Yan GANG ; Yalun WANG

Affiliations

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Keywords

ginseng polysaccharides; anti-tumor activity; structure-activity relationship

Country

China

Language

Chinese

Abstract

Objective:To test the effect of ginseng polysaccharides on anti?tumor activity. Method: The cell inhibitory rates were detected by MTT assay. Results: The starch?like glucan ( WGPN) and the AG type pectin ( WGPA?2?RG) had no effect on tumor cells, the AG+HG type pectin ( WGPA?4?RG) and the HG type pectin ( WGPA?3?HG, WGPA?1?HG) showed stronger effect on tumor cells. Conclusion:Different types of ginseng polysaccharides have different antiproliferation. A neutral fraction WGPN has no inhibition, while ginseng pectin exertes variable inhibition.