Korean Journal of Hematology  2009;44(3):144-147

doi:10.5045/kjh.2009.44.3.144

A Case of Acute Myeloblastic Leukemia in a Patient with Behcet's Disease.

Dong Hyeok CHA 1 ; Seon Kyeong KIM ; Hyo Jeong KIM ; Naria LEE ; Hyeong Seok NAM ; Bo Gwang CHOI ; Hye Won LEE ; Seong Geun KIM ; Young Jin CHOI ; Joo Seop CHUNG ; Goon Jae CHO

Affiliations

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Keywords

Behcet's disease; Acute myeloblastic leukemia

Country

Republic of Korea

Language

Korean

Abstract

Behcet's disease is a relapsing inflammatory disorder characterized by vasculitis of unknown cause and has been reported rarely in association with malignant diseases. In most cases the autoimmune nature of Behcet's disease and the long-term immunosuppressive therapy for disease control have been proposed to be responsible for malignant transformation. Although a few cases of various solid tumor and myelodysplastic syndrome have been reported in association with Behcet's disease, acute leukemia has seldom been associated with Beh?et's disease in Korea. We report a case of 38-year-old man with acute myeloblastic leukemia association with a Behcet's disease who had not received long-term treatment.