Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 2006;0(05):-

Effects of early Xuebijing injection(血必净注射液) treatment on the change of prognosis in patients with multiple traumas

Jing-En WANG ; Jin-Fang CAI ; Zhi-Hua WANG ; Xiao-Hong XIE ; Wei QU ; Nian ZHU ; Bo GAO ; Ying SHENG ; Jia-shi GU

Keywords

multiple trauma; Xuebijing injection; sepsis; multiple organ dysfunction syndrome; case fatality

Country

China

Language

Chinese

Abstract

15 scores were randomly divided into therapeutic group (30 cases)and control group(30 cases).The two groups were treated with the same conventional therapy. From the 1st day of admission,Xuebijing injection 80 ml was given by intravenous drip once for every 12 hours for 7 days to the therapeutic group.The level of tumor necrosis factor-?(TNF-?),interleukin-1?(IL-1?),IL-6,IL-10,and APACHEⅡscore were tested on 1,3,5 and 7 days after admission.The case fatality and incidences rates of sepsis and MODS in both groups were recorded.Results Compared with the control group,APACHEⅡscore,TNF-?,IL-1?,IL-6 and IL-10 of the therapeutic group were lower significantly on the 3rd day after admission,especially on the 5th day(all P