Korean Journal of Clinical Neurophysiology  2015;17(1):31-34

doi:10.14253/kjcn.2015.17.1.31

A Case of Squamous Cell Lung Cancer Representing as Guillain-Barre Syndrome Associated with Monospecific Anti-GD1b IgG.

Yeshin KIM 1 ; Seongheon KIM

Affiliations

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Keywords

Guillain-Barre syndrome; Paraneoplastic syndrome; Anti-GD1b antibody

Country

Republic of Korea

Language

Korean

Abstract

We report a case with squamous cell lung cancer with concomitant Guillain-Barre syndrome (GBS) as a paraneoplastic syndrome. A 67-year-old patient who was previously diagnosed as metastatic squamous cell lung cancer developed mild symmetrical weakness, paresthesia and sensory ataxia. Nerve conduction study showed sensorimotor polyneuropathy. Analysis of cerebrospinal fluid showed high tilter for monospecific anti-GD1b IgG antibody without onconeuronal antibodies. After treatment with intravenous immunoglobulin, the patient's symptoms improved.