Objective:To discuss the methods and meaning of constructing and applying the standard disease model based on pharmacoeconomie evaluation in China.Methods:Methods of theoretical analysis and qualitative research were applied.Results:There was feasible technology and methods for constructing and applying the standard disease model hased on pharmacoeconomic evaluation,which had great significance on improving the efficiency and reliability of the pharmacoeconomic evaluation.However,the major challenges came from the accumulation and integration of basic data.Conclusion:It was necessary and important to apply standard disease model in pharmacoeconoc evaluation,but the data gap must be filled.