Objective:To study the interaction between health human capital investment and urbanization in China.Methods:Through the establishment of a comprehensive evaluation index system of health human capital investment and urbanization,the coupling model of physics was applied to carry out an empirical analysis on the eoupling of health human capital investment and urbanization from 1995-2015.Results:The investment of health human capital and the level of urbanization showed a slow upward trend,but the development level of them was not high;the two systems showed the trend of co-evolution,but still showed low coupling strength and low coordination level;the coupling strength between the two increased first and then remained stable,the coordination increased gradually;health expenditure made the greatest contribution in health human capital investment system,while the urbanization made the greatest contribution in city system.Conclusion:It needed to increase investment in bealth human capital,while focusing on health human capital investment,so as to better play the role of health expenditure on the promotion of urbanization.