Journal of International Pharmaceutical Research 2017;44(8):778-782

doi:10.13220/j.cnki.jipr.2017.08.006

Biodegradable microneedles applied in the transdermal drug delivery:research advances

feng Qian HUANG 1 ; qing Hua LIN ; xin Bin PENG ; zhou Fang SHUAI

Affiliations

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Keywords

microneedle; biodegradable material; transdermal drug delivery

Country

China

Language

Chinese

Abstract

Microneedle is a painless and minimally invasive transdermal drug delivery. It can enhance the permeability of skin for macromolecular drugs by puncturing and creating a micron-level drug delivery channel in the skin. The biodegradable microneedles aim to solve the problem that nondegradable-material microneedles may break under skin and cause adverse reaction. This article pro?vides an overview of the characteristics of biodegradable microneedles,the biodegradable materials used,its recent research progress, the development status and the tendency.