Objective To explore the changes of hemodynamics in acute kidney injury (AKI) after acute severe Stanford type A aortic dissection.Methods Forty patients with acute Stanford A type aortic dissection were enrolled.Arterial peak systolic velocity (PSV),end diastolic velocity (EDV),pulsative index (PI),resistive index (RI),Serum creatinine (SCr) and urine volume were recorded and measured 1 day before operation,immediately after operation (enter the intensive care unit),6 h after operation,24 h after operation and 48 h after operation.Patients were divided into AKI group and non-AKI.group taking AKIN as a standard.Results Twenty-seven patients were in AKI group and 13 were in non-AKI group.The EDV,PI and RI had significantly differences between AKI group and non-AKI group at 6 h,24 h after operation.Correlation analysis showed that EDV negatively correlated with SCr (r=-0.508,P=0.001),while PI,RI positively correlated with SCr (r=0.411,0.443,P=0.009,0.005).Conclusion EDV,PI and RI in the interlobular arteries can be used to predict AKI early in the interosseous arteries,and the optimal time for ultrasonic measurement of renal arterial hemodynamics to predict is at 6 h and 24 h after operation.