Practical Oncology Journal 2017;31(5):472-476

doi:10.11904/j.issn.1002-3070.2017.05.017

Current status of anti-angiogenesis therapy for non-small cell lung cancer

Xin DAI 1

Affiliations

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Keywords

Anti-angiogenesis; Non-small cell lung cancer; VEGF; TKI

Country

China

Language

Chinese

Abstract

Angiogenesis is the physiological process of generating new blood vessels from existing net-works.In the tumor microenvironment,the dynamic balance of a growing tumor facilitates the transition to persis-tent angiogenesis.Antiangiogenic drugs have been used in a variety of solid tumors,including lung cancers,by re-sisting tumor angiogenesis and inhibiting tumor growth,since human recognized its ability.In this paper,recent re-search status of tumor angiogenesis and non-small cell lung cancer anti-angiogenesis are reviewed in details.