Journal of Bacteriology and Virology  2015;45(1):51-53

doi:10.4167/jbv.2015.45.1.51

ISAba15 Inserted into Outer Membrane Protein Gene carO in Acinetobacter baumannii.

Dae Hun KIM 1 ; Kwan Soo KO

Affiliations

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Keywords

Carbapenem; Insertion sequence (IS); Antimicrobial resistance

Country

Republic of Korea

Language

English

Abstract

We identified ISAba15 inserted into the carO gene in an Acinetobacter baumannii isolate. The insert disrupted the lpxD gene, resulting in colistin resistance in A. baumannii. Persistence in carbapenem resistance in A. baumannii isolates with an intact carO gene indicates that loss of the encoded CarO may play a minor role in carbapenem resistance.