Korean Journal of Hepato-Biliary-Pancreatic Surgery  2004;8(3):202-205

Nesidioblastosis with Hyperinsulinemic Hypoglycemia in Adult.

Young Bin LEE 1 ; Chul Nam KIM ; Tae Gil HUR ; Gi Hong KIM ; Myoung Soo LEE ; Surg Hyo CHANG

Affiliations

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Keywords

Nesidioblastosis; Hyperinsulinemic Hypoglycemia

Country

Republic of Korea

Language

Korean

Abstract

Nesidioblastosis is a term that describes the prolonged differentiation of islets of Langerhan's cells from the epithelium of the pancreatic duct. Nesidioblastosis is a primarily childhood disease, which is often associated with hyperinsulinemic hypoglycemia, but rarely found in adults. A 62-year-old man with hyperinsulinemic hypoglycemia complained of general weakness and mental change while fasting. Abdominopelvic CT, celiac angiography, intra-arterial calcium stimulation test and endoscopic ultrasonography did not reveal any tumor in the pancreas. A subtotal pancreatectomy (nearly 80% of pancreas was removed) was then carried out. He was diagnosed with nesidioblastosis inform the pathology after the operation. Herein, our experience of a 62-year-old Nesidioblastosis patient is reported.