The Journal of the Korean Society for Transplantation  2016;30(4):190-193

doi:10.4285/jkstn.2016.30.4.190

Calcineurin Inhibitor Induced Multiple Infarctions.

Hae Bong JEONG 1 ; Jeong Min KIM ; Il Han YU ; Jae Han BAE ; Oh Sang KWON ; Kwang Yeol PARK

Affiliations

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Keywords

Tacrolimus; Acute cerebral infarction; Kidney transplantation

Country

Republic of Korea

Language

Korean

Abstract

Tacrolimus is the most commonly used immunosuppressant after kidney transplantation. Here, we report a patient with multiple cerebral infarctions during tacrolimus treatment after kidney transplantation. A 54-year-old female was admitted due to sudden onset right leg weakness. Brain magnetic resonance imaging (MRI) showed multiple acute infarctions but normal vasculature. Evaluations of cardiac embolism were unremarkable. After 8 months, her weakness progressed and follow-up brain MRI showed additional multiple infarctions. We changed here medication from tacrolimus to mycophenolate mofetil, and her symptoms improved gradually.