Journal of the Korean Association of Oral and Maxillofacial Surgeons  2011;37(1):67-71

doi:10.5125/jkaoms.2011.37.1.67

Low-grade myxofibrosarcoma in the mandible: a case report.

Ji Hoon PARK 1 ; So Young CHOI ; Tae Geon KWON ; Chin Soo KIM

Affiliations

+expand

Keywords

Myxofibrosarcoma; Mandible; Recurrence; Biologic grading

Country

Republic of Korea

Language

Korean

Abstract

Myxofibrosarcoma, also known as a myxoid variant of a malignant fibrous histiocytoma (MFH), is one of the most common sarcomas in the extremities of elderly people. The lesion is characterized by a high frequency of local recurrence but is uncommon in the head and neck regions. Low-grade myxofibrosarcoma, which is commonly misinterpreted as being benign, has a tendency for histological and biological progression in local recurrences, highlighting the importance of an accurate diagnosis and wide surgical excision of the primary lesion. We report a rare case of low-grade myxofibrosarcoma of the mandible located in the left mandibular body and angle area. The tumor was first diagnosed as a myxofibroma and was resected initially. After the final biopsy the patient underwent combined chemo-radiotherapy. The progress of the patent was uneventful until the one year follow up.