Study on 335 cases underwent endoscopic biopsies. The results showed that: The rate of Helicobacter pylori (HP) infection in gastric ulcer patients that had clinical symptoms were 63%, highest in group of 31 to 50 years old. Inflammatory and ulcer lesions were in antropyloric area, and the rate of HP (+) was highest in this area. In comparison with endoscopic diagnosis, the highest ratio of HP was in gastric ulcer accompany with duodenal bulb ulcer, and lowest rate was in acute inflammation. There was no significant difference in infected frequency between male and female. However, moderate and severe infections (Hp2+, Hp3+) in men were more common than those in women