Journal of the Korean Neurological Association  2002;20(1):79-81

Three Cases of Anticonvulsant Hypersensitivity Syndrome Associated with Lamotrigine.

Yong Won CHO 1 ; Hyung LEE ; Sung Il SOHN ; Doo Kyo JUNG ; Jeong Geun LIM ; Sang Doe YI

Affiliations

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Keywords

Anticonvulsant hypersensitivity syndrome; Lamotrigine

Country

Republic of Korea

Language

Korean

Abstract

Among the various side effects of anticonvulsant medication, the anticonvulsant hypersensitivity syndrome (AHS) is underrecognized. This condition developed frequently with aromatic anticonvulsants, but with new antiepileptic drugs as well. We experienced three lamotrigine-induced AHS cases with symptoms such as fever, rash, leukopenia, eosinophilia and lymphadenopathy, which subsided after withdrawal of lamotrigine.