Journal of Breast Disease 2017;5(1):28-34

doi:10.14449/jbd.2017.5.1.28

Synchronously Diagnosed Gastric Metastasis from Invasive Lobular Breast Carcinoma, Mimicking Primary Gastric Carcinoma.

Young Duck SHIN 1 ; Seung Myoung SON ; Young Jin SONG ; Sung Su PARK ; Young Jin CHOI

Affiliations

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Keywords

Breast; Carcinoma; Lobular; Neoplasm metastasis; Stomach

Country

Republic of Korea

Language

Korean

Abstract

Gastric metastasis from invasive lobular breast carcinoma is rare. Mostly gastrointestinal metastasis presents as one among multiple metastases, several years after primary diagnosis of breast carcinoma. Herein, we report a synchronously diagnosed gastric metastasis from invasive lobular carcinoma, mimicking primary gastric linitis plastica with pyloric obstruction. We reviewed clinical and pathological findings of gastric carcinoma metastatic from the breast. In particular, we focused on immunohistochemical studies of selected antibodies, including those for estrogen receptors, gross cystic disease fluid protein-15, and caudal-type homeobox transcription factor 2, for accurate differential diagnosis. Clinical suspicion, repeat endoscopic biopsy, and detailed histological analysis including immunohistochemistry are necessary for diagnosis of gastric carcinoma metastatic from the breast.