Journal of Practical Medicine  2003;442(2):73-75

In vitro IGG and IGM producting cells in leprosis patients with ND-BSA, a semisynthetic antigene of mycobacteria leprae

Vu Tan Trao

Keywords

Leprosis

Country

Viet Nam

Language

Vietnamese

Abstract

Leprosy; Patients; Mycobacterium leprae; cells; Mycobacterium leprae; Antigens 18 leprosis patients treated in the Central Institute of Demato-venerlogy, 12 leprosis patients' children, 6 health workers in leprosis sanatoria enrolled medical students were enrolled in the study. ELISA technique was used to determine the process of production of specific antibody to ND-BSA in vitro. IgM antibody was detected in the culture of leprosis sample culture as well as of persons contacting with the patient and health persons. In each individual there can be IgM reaction, or only IgG and IgG together with IgM reaction to this antigene. All subjects who have IgG reaction to ND-BSA have transformed lympho response in vitro to ultracrushed M-leprae antigene and ND-BSA