Chinese Ophthalmic Research  2009;27(11):1044-1047

Research advance in application of stem cells in optic nerve regeneration

Jingxue, ZHANG ; Ningli, WANG ; Jianmin, MA

Keywords

retinal ganglion cell; stem cell; optic nerve regeneration; transplantation

Country

China

Language

Chinese

Abstract

Lots of blinding diseases are caused by retinal ganglion cells apoptosis, but there is no the effective and ideal therapy in clinic currently. Recent study showed that stem cells can be an alternative renewable source of retinal ganglion cells, and they may be potential to repair the visual function. These results provide a new model of optic nerve regeneration for the treatment of these blinding diseases. But, some problems in clinical applications are waiting for further solving. Applications of stem cells in optic nerve regeneration is reviewed in this paper.