Obstetrics & Gynecology Science  2015;58(5):405-408

doi:10.5468/ogs.2015.58.5.405

Prenatal diagnosis of congenital mesoblastic nephroma.

A Young DO 1 ; Jung Sun KIM ; Suk Joo CHOI ; Soo Young OH ; Cheong Rae ROH ; Jong Hwa KIM

Affiliations

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Keywords

Drug therapy; Nephroma, mesoblastic; Pregnancy; Prenatal diagnosis; Renal tumor

Country

Republic of Korea

Language

English

Abstract

Congenital mesoblastic nephroma is a rare renal tumor that is diagnosed during pregnancy and is associated with polyhydramnios, prematurity, and neonatal hypertension. Differential diagnoses include Wilms tumor, adrenal neuroblastoma, and other abdominal tumors. We report a case of congenital mesoblastic nephroma detected by prenatal ultrasonography as a large fetal renal mass with polyhydramnios at 32 weeks of gestation. Ultrasonography showed a 6x6-cm complex, solid, hyperechoic, round mass in the right kidney. At 35 weeks of gestation, the patient was admitted with preterm premature rupture of membranes and the baby was delivered vaginally. Postnatal ultrasonography and computed tomography showed a heterogeneous solid mass on the right kidney. At the end of the first week of life, a right nephrectomy was performed and subsequent pathological examination confirmed a cellular variant of congenital mesoblastic nephroma with a high mitotic count. Postoperative adjuvant chemotherapy was administered. The newborn was discharged in good condition.