International Journal of Cerebrovascular Diseases 2017;25(3):228-232

doi:10.3760/cma.j.issn.1673-4165.2017.03.007

Cold wave-induced stroke: the evidence from studies in stroke-prone hypertensive rats

Liming SHU ; Shuai TAN ; Hua HONG ; Ruxun HUANG

Keywords

Stroke; Brain Ischemia; Cerebral Hemorrhage; Subarachnoid Hemorrhage; Cold Temperature

Country

China

Language

Chinese

Abstract

Epidemiological data,clinical observation and animal experiments have shown that cold wave is closely associated with the onset of stroke.When a population with stroke etiology or risk factors is under pre-stroke state,they will have stroke under the influence of various inducing factors.Cold wave is the external factor that causes the body to enter the pre-stroke state and there are many possible mechanisms.The drug intervention of stroke-prone hypertensive rats at 1 week before the cold wave can reduce the occurrence of stroke during cold wave,suggesting that it is of great significance to conduct preventive intervention to the pre-stroke population before the cold wave coming.