Chinese Journal of Pharmacology and Toxicology 2017;31(6):696-700
doi:10.3867/j.issn.1000-3002.2017.06.029
Reseach progress in long non-coding RNA and its toxicology
Danyan ZHANG ; Longlue JIA ; Jiangfeng GUO
Keywords
long non-coding RNA; microRNA; toxicology
Country
China
Language
Chinese
Abstract
A large number of studies have shown that long non-coding RNAs (IncRNAs) display abnormallity in organisms exposed to toxic chemicals,carcinogens and heavy metals.In this paper,the relationships between IncRNAs and microRNAs (miRNAs),the expressions of IncRNAs in organisms exposed to different exogenous toxic chemicals and the related toxicological mechanism are reviewed in order to provide reference for biological monitoring with IncRNAs in environmental toxicology.
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