Infectious pancreatic necrosis (IPN) is a challenging complication of acute pancreatitis and can lead to poor prognosis.Over the years,open necrosectomy has become the main treatment modality for IPN,but it will cause high incidence rate of complications and mortality rate.In recent years,with the rapid development of minimally invasive surgery,many scholars have performed minimally invasive treatment for IPN patients and achieved good outcomes.This article introduces five minimally invasive treatment techniques,i.e.,percutaneous catheter drainage,minimally invasive retroperitoneal necrosectomy,endoscopic drainage + necrosectomy,laparoscopic necrosectomy,and advanced therapeutic strategy,pointed out that different minimally invasive techniques had different indications,and minimally invasive therapies should be selected based on IPN patients' general conditions to improve their outcome.