Recent Advances in Ophthalmology 2017;37(5):484-487

doi:10.13389/j.cnki.rao.2017.0123

Role of epidermal growth factor in ocular diseases

Huixin SONG ; Jianfeng WU ; Hongsheng BI

Keywords

epidermal growth factor; ocular diseases; cornea; retina; sclera

Country

China

Language

Chinese

Abstract

Epidermal growth factor (EGF) is a multifunctional growth factor,which is widely expressed in most ocular tissues including cornea,retina and sclera.It may regulate the growth and proliferation of various ocular cells with the interaction of epidermal growth factor receptor in vitro or in vivo.This article reviews the role of EGF in pathological and physiological processes of ocular diseases,including corneal injury,retinal proliferative diseases,myopia,pterygium,glaucoma,cataract,and eye tumors.