Chinese Journal of Rehabilitation Theory and Practice 2017;23(5):548-552
doi:10.3969/j.issn.1006-9771.2017.05.012
Role of Dishevelled in Neurogenesis (review)
Zhimin WANG ; Caiqin MEI
Keywords
Dishevelled; Wnt signaling; neurogenesis; review
Country
China
Language
Chinese
Abstract
Dishevelled (Dvl) is a kind of protein widely existing in human tissue, containing three structural domains:Dishevelled and Axin (DIX);postsynaptic density protein-95, disc large tumour suppressor, zonula occludens-1 (PDZ);and Dishevelled, Egl-10 and pleck-strin (DEP). Dvl participates in the Wnt signaling through different structure domains to play a role in nervous system development and neu-rogenesis after nerve injury.
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