Chinese Journal of Rehabilitation Theory and Practice 2017;23(5):553-557
doi:10.3969/j.issn.1006-9771.2017.05.013
Advances of Molecular Mechanisms on Obesity Inducing Muscle Atrophy (review)
Lin LUO ; Jinpeng YANG ; Songtao WANG ; Xin LIAO ; Wei ZHAN
Keywords
obesity; muscle atrophy; signal pathway; review
Country
China
Language
Chinese
Abstract
Obesity is becoming a chronic epidemic worldwide. Persistent obesity, in addition to triggering changes in skeletal muscle function and structure, may also lead to the occurrence of skeletal muscle atrophy, that maybe associate with autophagy and ubiquitin protea-some, interleukin-6, leptin, adiponectin, interleukin-10, tumor necrosis factor-alpha, growth hormone, angiotensin II, glucocorticoid, ad-vanced glycation end-product and myostatin, etc.
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