Chinese Journal of Gastroenterology 2017;22(9):565-568

doi:10.3969/j.issn.1008-7125.2017.09.012

Advances in Study on Relationship Between LncRNA and Inflammatory Diseases

Xinyu PEI ; Zonghao CHEN ; Yu ZHOU

Keywords

Inflammatory Disease; Long Non-Coding RNA; Inflammation; Inflammatory Bowel Diseases

Country

China

Language

Chinese

Abstract

Long non-coding RNA (lncRNA)is a non-coding RNA which lacks a complete open reading frame (ORF)and plays an important role in biological processes such as cell proliferation,differentiation and apoptosis. At present,expression of lncRNA has been found to be abnormal in inflammatory reaction and inflammatory diseases. It might be involved in the development and progression of inflammatory diseases via regulating the expression of multiple genes and activation of signaling pathways. This article reviewed the progress in study on relationship between lncRNA and inflammatory diseases.