Chinese Journal of Medical Physics 2010;27(2):1704-1707,1720

doi:10.3969/j.issn.1005-202X.2010.02.002

Dosimetric Comparison of Inverse Three-Dimensional Conformal Radiotherapy and Intensity Modulated Radiotherapy for Non-Ssmall Cell Lung Cancer

Fuli ZHANG ; Weidong XU ; Junmao GAO ; Jianping CHEN ; Ping WANG ; Mingmin ZHENG

Keywords

inverse three-dimensional conformal radiotherapy; intensity modulated radiotherapy; non-small cell lung cancer

Country

China

Language

Chinese

Abstract

Objective: To compare inverse three-dimensional conformal radiotherapy (Inv 3D-CRT) and intensity modulated ra-diotherapy (IMRT) for non-small cell lung cancer. Methods: For a cohort of 10 patients, Inv 3D-CRT and three groups of IMRT plannings were designed for per patient. The prescribed dose was 60 Gy/2 Gy/30f, 95% of the planning target volume received this dose. Dose was computed with a commercially available TPS using convolution/superposition (CS) algorithm. Plans were compared according to the PTV_(95)V_(20) ratio (PTV_(95)V_(20)) and D_(max)-D_(min). Results: Compared with Inv 3D-CRT, the PTV_(95)V_(20) ratio of three groups of IMRT increased by 1.08 (P = 0.014), 0.72 (P = 0.089) and 0.42 (P = 0.318), respectively. Conclusions: For NSCLC, IMRT can reduce the dose to the lungs compared with inverse 3D-CRT by improving the conformity of the plan and is worth spreading in clinical work.