Vascular Specialist International  2016;32(2):65-71

doi:10.5758/vsi.2016.32.2.65

Recurrent Arterial Thrombosis as a Presenting Feature of a Variant M3-Acute Promyelocytic Leukemia.

Pranit N CHOTAI 1 ; Kalenda KASANGANA ; Abhinav B CHANDRA ; Atul S RAO

Affiliations

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Keywords

Acute limb ischemia; Cold leg; Arterial thrombosis; Acute promyelocytic leukemia; Acute myeloid leukemia-M3

Country

Republic of Korea

Language

English

Abstract

Acute limb ischemia (ALI) is a common vascular emergency. Hematologic malignancies are commonly associated with derangement of normal hemostasis and thrombo-hemorrhagic symptoms during the course of the disease are common. However, ALI as an initial presenting feature of acute leukemia is rare. Due to the rarity of this presentation, there is a scarcity of prospective randomized data to optimally guide the management of these patients. Current knowledge is mainly based on isolated cases. We report our experience managing a patient who presented with ALI and was found to have occult leukemia. A review of all cases with ALI as a presenting feature of acute leukemia is also presented.