Journal of International Pharmaceutical Research 2014;(5):516-520,521
doi:10.13220/j.cnki.jipr.2014.05.002
Complement system and tumor:research progress Complement system and tumor:research progress
Chang NING ; Wenwei CHEN ; Yan LI ; Guojiang CHEN
Keywords
complement; tumor; growth factor; signal pathway; angiogenesis
Country
China
Language
Chinese
Abstract
Complement system is an important component of innate immunity and has been recognized as an effective means to inhibit tumor. However,in last decades,accumulating studies showed unexpected results that the complement components and their activation products could promote development of malignancies by secreting growth factors,activating signal pathway and promoting tumor angiogenesis. Herein,the relationship between the complement system and tumor is reviewed.
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