Journal of the Korean Society of Neonatology  2011;18(2):391-394

doi:10.5385/jksn.2011.18.2.391

A Case of Neonatal Lupus Erythematosus and Retrospectively Diagnosed with Asymtomatic Maternal Lupus Erythematosus.

Ji Yeon HAN 1 ; Jung Min YOON ; June Bum KIM ; Jae Woo LIM ; Young Hyuk LEE ; Kyong Og KO

Affiliations

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Keywords

Neonatal lupus erythematosus; Erythema multifome; Asymptomatic; Maternal lupus

Country

Republic of Korea

Language

Korean

Abstract

Neonatal lupus erythematosus (NLE) is a rare disease characterized by typical clinical features and the transplacental passage of maternal autoantibodies, particularly anti-SSA/Ro. The major clinical manifestations are cutaneous lupus lesions, congenital heart block, hematological disorders, and hepatobiliary diseases. We report a case of NLE presenting with multiple round and oval target-like erythematous skin lesions and abnormal liver function, born to a clinically asymptomatic mother whose diagnosis was made retrospectively only after her newborn's diagnosis. Both the infant and the mother were positive for the anti-SSA/Ro and anti-SSB/La antibodies.