Journal of the Korean Neurological Association  1988;6(2):261-267

A Case of Delayed Peripheral Polyneuropathy Induced by Organophosphorus Intoxication.

Won Young JUNG 1 ; Myung Sik LEE ; Il Saing CHOI ; Je Geun CHI

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Country

Republic of Korea

Language

Korean

Abstract

Delayed peripheral polyneuropathy caused by organophosphorus intoxication is not uncommon. This is a case report of 32 years old female with peripheral polyneuropathy which is appeared two weeks after organophosphorus poisoning. It is characterized by calves pain followed by minmal sensory change and predominant motor weakness affecting the distal part of the limbs. The electrophysiologic and pathologic studies support the clinical diagnosis. The exact pathogenesis is still debated, but phosphorylation of neurotoxic esterase (NTE), followed by "aging" process was suspected to play a role in the development of axonal degeneration.