Chinese Journal of Vaccines and Immunization 2008;0(01):-

Investigation of VP_7 From Rotaviruse Strains in Ningbo City,China

Yan FU ; Hong GAO ; Jianyi LIU

Keywords

Rotavirus; VP7; Sequence analysis

Country

China

Language

Chinese

Abstract

Objective To know the currently prevalent genotype of rotavirus strains in Ningbo City,which will help to the study of vaccine of group A rotavirus.Methods The VP7 fragments were amplified by RT-PCR and sequence analysis was conducted from 2 of the 11 virus strains.Results VP7 amino acid sequences homogeneity of the two strains Ningbo 06-1 and Ningbo 06-3 was 90.2%.They all shared higher amino acid sequences homogeneity with G1 strain Wa(95.1% and 87.7%,respectively)than with other serotypes(G types)rotavirus(