On recently years,the tuberculosis shows the characteristic of higher incidence、 infection、drug-resistance、and Morbidity。However,the emphasis and difficult is preventing and controling of multidrug resistant tuberculosis.Its nosocomial and societal causes of occuring and prevailing were analyzed and control measures from seven facets were expounded in this article.Those include prevention knowledge widely,strengthen management and supervision of floating population,improve ability of diagnosis and therepy,develop combinasion treatment of traditional chinese medicine and western medicine and other assistant treatment, prevent community and nosocomial infection,perfect the drug-resistant surveillance system,carry out the study of new drug 、measure and treatment to anti-tuberculosis actively.