Chinese Journal of Hypertension 2006;0(08):-

Serum Free Fatty Acids Composition, Waist/Hip Ratio and insulin activity in Patients with Essential Hypertension

Shun WANG ; Aiqun MA ; Shaowu SONG ; Qinghai QUAN ; Xiaohui ZHENG ; Xinfeng ZHAO

Keywords

Free fatty acid; Essential hypertension; ?6 desaturase; ?-linolenic Acid

Country

China

Language

Chinese

Abstract

Objective To investigate the relationship of fasting serum FFA composition with central obesity, hypertension, insulin resistance, levels of serum zinc and age, gender-related differences. Methods Serum FFA were determined by high performance liquid chromatogram in 232 commuity|based subjects aged between 35 and 55 years: 109 hypertensives, 123 normotensives. Results Multivariate stepwise linear regression models and correlation analysis showed that serum FFA composition (including levels of n3PUFA, P/S ratio, C20:5/C18:3, C22:6/C20:5 and C20:4/C18:2 ratio) were linearly correlated with waist/ hip ratio, insulin sensitivity index, levels of serum zinc and related to the habit of diet (all P